Indianapolis Colts left tackle Anthony Castonzo (knee) has been ruled out for the rest of his team’s Week 12 contest against the Titans. It’s a big loss for this Colts offense, which will now have more trouble keeping quarterback Philip Rivers upright. If Castonzo misses time, drop Colts offensive players a few spots in your rankings. Source: NFL Network – Tom Pelissero

Atlanta Falcons wide receiver Olamide Zaccheaus (toe) is questionable to return to Sunday’s game against the Las Vegas Raiders. He has one catch for 11 yards. With Julio Jones out as well, Russell Gage would benefit if Zaccheaus can’t return. Source: Atlanta Falcons

Miami Dolphins wide receiver Malcolm Perry (chest) is questionable to return to Sunday’s game against the New York Jets. Perry set career highs in targets (five), catches (three) and yards (23) last week, but hasn’t been much of a factor in this offense this season, so his absence from this game shouldn’t change much in terms of fantasy outlooks. Source: Miami Dolphins

Buffalo Bills tight end Tyler Kroft appears to be a healthy scratch for Sunday’s contest against the Los Angeles Chargers. Dawson Knox will see most of the tight end work against a Chargers Defense that can definitely be exploited, making Knox an intriguing TE2 streamer. Knox hasn’t had more than two catches in a game yet this year though, so don’t get your hopes up

Atlanta Falcons tight end Hayden Hurst (ankle) is active for Sunday’s game against the Raiders. With Julio Jones (hamstring) out, there could be some increased work for Hurst this week. Before last week’s zero catch performance against the Saints, Hurst had seen seven targets or more in three consecutive games, so there should be a decent floor here, even if Hurst hasn’t had many huge

With New York Jets quarterback Sam Darnold back at quarterback this week, the team will also see head coach Adam Gase take back over playcalling duties. It’ll be interesting to see if Gase changes anything for the Jets. Considering his reputation as kryptonite to offensive players, we wouldn’t be staking our fantasy hopes on Darnold or any of the Jets players this week, though rookie

New England Patriots running back Sony Michel was apparently a healthy scratch in Week 11 after coming off the Injured Reserve, but he’s active for Week 12 against the Panthers. This is likely just the result of Rex Burkhead (knee) being out, and Michel won’t see much work. It’s possible his return cuts a little into Damien Harris‘s workload, but Harris should still be a

Minnesota Vikings tight end Irv Smith Jr. (groin) and wide receiver Adam Thielen (COVID-19) are both out for Minnesota’s Week 12 contest against the Carolina Panthers. The Vikings will have to rely more on rookie wide receiver Justin Jefferson in this one, who’s a low-end WR2 play. Tight end Kyle Rudolph has some streaming or DFS potential as well. Source: Minnesota Vikings

Cincinnati Bengals running back Giovani Bernard (concussion) has been cleared to play against the Giants in Week 12 and is officially active. With Brandon Allen starting at quarterback, Bernard should see plenty of work, though Samaje Perine will likely siphon off some of his usage. Bernard’s a low-end RB2 play this week. Source: Cincinnati Bengals – Marisa Contipelli

Indianapolis Colts quarterback Philip Rivers (toe) is active for Sunday’s game against the Tennessee Titans. After missing practice time during the week, there was some concern for Rivers, but he’ll be good to go. The Titans Defense has had some issues this season and Rivers already had a 300-yard game against them, so if you’re in need of a streamer at the quarterback position or

Jacksonville Jaguars quarterback Gardner Minshew II (thumb) will miss his fourth consecutive game on Sunday when the Jags face the Cleveland Browns. Mike Glennon will start while Jake Luton, who started the past three games, will back Glennon up. Minshew was struggling when healthy, but it’s become clear that this passing offense barely functions with Luton under center. Glennon is unlikely to change that. Source:

As expected, Miami Dolphins quarterback Tua Tagovailoa (thumb) is inactive for Sunday’s game against the Jets and will potentially miss more time as well. Tagovailoa is 3-1 as a starter, but has struggled at times to move the ball. Ryan Fitzpatrick slides into the starting role this week and should upgrade this offense’s fantasy upside a little bit. Consider Fitzpatrick a strong streaming option against

Atlanta Falcons wide receiver Julio Jones (hamstring) is inactive for his team’s Week 12 contest against the Las Vegas Raiders. Jones was slowed down last week with the hamstring issue and ended up playing just 35 percent of Atlanta’s snaps. Calvin Ridley (foot) won’t be at 100 percent, but should see plenty of targets in this matchup and is a strong WR2 play. Russell Gage

Denver Broncos wide receiver Kendall Hinton has officially been elevated to the team’s active roster and is set to start at quarterback on Sunday against the New Orleans Saints. A quarterback for part of his time at Wake Forest, Hinton isn’t someone you should look to play at quarterback this week, but on platforms where he still has wide receiver eligibility, his projected role gives

Miami Dolphins quarterback Tua Tagovailoa (thumb) is not expected to start in Week 12, though there’s nothing broken in his injured thumb. Tagovailoa jammed his thumb against a helmet during practice, but it appears that he avoided the worst, as he is dealing with swelling and weakness in the thumb. However, the rookie could miss more than just one contest as he deals with the

Denver Broncos wide receiver Jerry Jeudy (ankle, Achilles) is expected to suit up in Week 12 against the Saints. Jeudy was limited on Friday, though it’s looking like he’ll play after toughing out the ankle injury last week. It’s certainly a concern, though the bigger worry is the quality of targets that Jeudy will see from practice squad wide receiver Kendall Hinton, who was thrust

The San Francisco 49ers could end up playing the remainder of their home games in Arizona due to new COVID-19 restrictions in Santa Clara, home of Levi’s Stadium. The county of Santa Clara has banned all contact sports and implemented a 14-day quarantine for anyone traveling into the area from 150 miles away. Fortunately, the 49ers’ division rivals may be offering them some help, as

Indianapolis Colts quarterback Philip Rivers (toe) is expected to suit up for Sunday’s pivotal divisional matchup with the Titans. Rivers was listed as questionable after Friday’s practice, though head coach Frank Reich indicated it was a good session for the veteran quarterback. With Rivers close to full strength, the Colts may have to rely on his arm a bit more with Jonathan Taylor on the

Cincinnati Bengals running back Giovani Bernard (head) is expected to take the field on Sunday against the Giants. A full practice session on Friday had Bernard looking good for the Week 12 contest, though it’s always nice to get further confirmation closer to kickoff. Look for the veteran back to be among the list of Bengals’ actives ahead of the matchup with New York. The

San Francisco 49ers cornerback Richard Sherman (calf) is expected to make his return to the field in Week 12 against the Rams. Sherman hasn’t played since Week 2 due to the calf injury, but the San Francisco secondary has held strong for the most part, ranking fifth against the pass this year. The former All-Pro will be a welcome addition, however, as Rams’ receivers Robert