The San Francisco 49ers Defense may have sustained significant blows by losing Nick Bosa (knee) and Solomon Thomas (knee) for the remainder of the season in Week 2, but that didnt stop them from looking strong against the Giants in Week 3. Looking ahead, theyll face a rocky Eagles offense that has had to answer questions about Carson Wentzs starting quarterback status since Sunday, with a Dolphins squad two weeks away that is quarterbacked by Ryan Fitzpatrick, who has tossed three interceptions this season. While their status as the preeminent defensive unit may have taken a step back, San Francisco still unquestionably has a defense worth rostering and deploying on a weekly basis until the group proves otherwise.